A fierce debate is underway over the legacy of Darwin’s theories of evolution. It is time to move on from Darwinism and Neo-Darwinism, according to Professor Denis Noble, Emeritus Professor of Physiology and Fellow of Balliol College. We need wider, integrative, approaches, involving proteins and RNAs as well as genes, he explains in this interview with Dr Paul Flather of Mansfield College and President of The Forum for Philosophy.